Association between serotonin 5-HT-2C receptor gene (HTR2C) polymorphisms and obesity- and mental health-related phenotypes in a large population-based cohort.

doi:10.1038/ijo.2009.292

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Article

Association between serotonin 5-HT-2C receptor gene (HTR2C) polymorphisms and obesity- and mental health-related phenotypes in a large population-based cohort.

International journal of obesity (2005) - 1 Jun 2010

Vimaleswaran K S, Zhao J H, Wainwright N W, Surtees P G, Wareham N J, Loos R J F

Abstract excerpt

OBJECTIVE: Studies have shown that common single-nucleotide polymorphisms (SNPs) in the serotonin 5-HT-2C receptor (HTR2C) are associated with antipsychotic agent-induced weight gain and the development of behavioural and psychological symptoms. We aimed to analyse whether variation in the HTR2C is associated with obesity- and mental health-related phenotypes in a large population-based cohort. METHOD: Six...

Topics

Adult
Aged
Antipsychotic Agents
Body Mass Index
Body Weight
Depressive Disorder
Female
Genetic Variation
Humans
Male
Mental Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Obesity

Phenotype

Polymorphism, Single Nucleotide

Receptor, Serotonin, 5-HT2C

Surveys and Questionnaires

Source

Open in PubMed

Identifiers

PMID: 20065966
DOI: 10.1038/ijo.2009.292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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