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Article

Nuclear Control of Vascular Smooth Muscle Cell Plasticity during Vascular Remodeling.

The American journal of pathology - 1 Apr 2024

Ahmed Ibrahim A, Liu Mingjun, Gomez Delphine

Abstract excerpt

Control of vascular smooth muscle cell (SMC) gene expression is an essential process for establishing and maintaining lineage identity, contractility, and plasticity. Most mechanisms (epigenetic, transcriptional, and post-transcriptional) implicated in gene regulation occur in the nucleus. Still, intranuclear pathways are directly impacted by modifications in the extracellular environment in conditions of...

Topics

Humans
Phenotype
Vascular Remodeling
Muscle, Smooth, Vascular
Cell Plasticity
Gene Expression Regulation
Myocytes, Smooth Muscle

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37820925
DOI: 10.1016/j.ajpath.2023.09.013
PMCID: PMC10988766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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