Article
Nuclear Control of Vascular Smooth Muscle Cell Plasticity during Vascular Remodeling.
The American journal of pathology - 1 Apr 2024
Ahmed Ibrahim A, Liu Mingjun, Gomez Delphine
Abstract excerpt
Control of vascular smooth muscle cell (SMC) gene expression is an essential process for establishing and maintaining lineage identity, contractility, and plasticity. Most mechanisms (epigenetic, transcriptional, and post-transcriptional) implicated in gene regulation occur in the nucleus. Still, intranuclear pathways are directly impacted by modifications in the extracellular environment in conditions of...
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