Article
Epigenetics and miRNA emerge as key regulators of smooth muscle cell phenotype and function.
Pulmonary pharmacology & therapeutics - 1 Feb 2013
Clifford Rachel L, Singer Cherie A, John Alison E
Abstract excerpt
Regulation of phenotypic plasticity in smooth muscle requires an understanding of the mechanisms regulating phenotype-specific genes and the processes dysregulated during pathogenesis. Decades of study in airway smooth muscle has provided extensive knowledge of the gene expression patterns and signaling pathways necessary to maintain and alter smooth muscle cell phenotype. With this solid foundation, the...
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