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Article

The Complex Role of Methylation in Regulating Vascular Smooth Muscle Cell Phenotypic States in Vascular Remodeling and Atherosclerosis.

Biomolecules - 2 Jun 2026

Basak Sanjana C, Gomez Delphine

Abstract excerpt

Vascular smooth muscle cell (VSMC) control of phenotypic states through regulation of contractile gene expression is critical for vascular homeostasis and for participation in pathological vascular remodeling, such as atherosclerosis. Cohorts of molecular and cellular processes, including transcriptional and post-transcriptional repression of VSMC contractile genes, context-dependent activation of pathological...

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Share to Atherosclerosis
Share to DNA Methylation
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Phenotype

Share to Vascular Remodeling

Source

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Identifiers

PMID: 42352292
DOI: 10.3390/biom16060825
PMCID: PMC13296941

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