Article
Influence of DNA Methylation on Vascular Smooth Muscle Cell Phenotypic Switching.
International journal of molecular sciences - 8 Mar 2024
Yorn Chanthong, Kim Hyunjung, Jeong Kyuho
Abstract excerpt
Vascular smooth muscle cells (VSMCs) are crucial components of the arterial wall, controlling blood flow and pressure by contracting and relaxing the artery walls. VSMCs can switch from a contractile to a synthetic state, leading to increased proliferation and migratory potential. Epigenetic pathways, including DNA methylation, play a crucial role in regulating VSMC differentiation and phenotypic flexibility. DNA...
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