Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Controlled release of cytokines using silk-biomaterials for macrophage polarization.

Biomaterials - 1 Dec 2015

Reeves Andrew R D, Spiller Kara L, Freytes Donald O, Vunjak-Novakovic Gordana, Kaplan David L

Abstract excerpt

Polarization of macrophages into an inflammatory (M1) or anti-inflammatory (M2) phenotype is important for clearing pathogens and wound repair, however chronic activation of either type of macrophage has been implicated in several diseases. Methods to locally control the polarization of macrophages is of great interest for biomedical implants and tissue engineering. To that end, silk protein was used to form...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aniline Compounds
Share to Biocompatible Materials
Share to Delayed-Action Preparations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-gamma

Share to Interleukin-4

Share to Microscopy, Electron, Scanning

Share to Solubility

Source

Open in PubMed Open full text

Identifiers

PMID: 26421484
DOI: 10.1016/j.biomaterials.2015.09.027
PMCID: PMC4605898

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Controlled release of cytokines using silk-biomaterials for macrophage polarization.PMID 26421484Read ↗

Controllable release of interleukin-4 in double-layer sol-gel coatings on TiO2 nanotubes for modulating macrophage polarization.Semantic proximity Read ↗

Defined Surface Physicochemical Cues Inhibit M1 Polarization of Human Macrophages Using Colloidal Self-Assembled Patterns.Semantic proximity Read ↗

Primary human macrophages are polarized towards pro-inflammatory phenotypes in alginate hydrogelsSemantic proximity Read ↗

Macrophage phenotype switch by sequential action of immunomodulatory cytokines from hydrogel layers on titania nanotubes.Semantic proximity Read ↗

Lentivirus delivery of IL-10 to promote and sustain macrophage polarization towards an anti-inflammatory phenotype.Semantic proximity Read ↗

AFM-IR probing the influence of polarization on the expression of proteins within single macrophages.Semantic proximity Read ↗

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds.Semantic proximity Read ↗

Modulation of mouse macrophage polarization in vitro using IL-4 delivery by osmotic pumps.Semantic proximity Read ↗

Remotely Temporal Scheduled Macrophage Phenotypic Transition Enables Optimized Immunomodulatory Bone Regeneration.Semantic proximity Read ↗

Modulation of Macrophage Phenotype by Biodegradable Polyurethane Nanoparticles: Possible Relation between Macrophage Polarization and Immune Response of Nanoparticles.Semantic proximity Read ↗

Engineering a reproducible 3D wound model with defined macrophage polarization and partial-thickness mechanical injurySemantic proximity Read ↗

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage PolarizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.