Article

Primary human macrophages are polarized towards pro-inflammatory phenotypes in alginate hydrogels

2019-11-08

Abstract excerpt

Dysregulated macrophage function is implicated in a wide range of disorders. In vitro hydrogel culture systems are often used as matrices to model and explore the effect of various external stimuli on macrophage polarization and behaviour. Here, we show that 3D alginate hydrogels are not “macrophage inert” and instead help to direct the maturation of primary human macrophages towards specific phenotypes. We compa...

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Literature Corpus work: 8a71e34c-179a-551c-8268-93376a66ba92
DOI: 10.1101/824391

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