Article
Defined Surface Physicochemical Cues Inhibit M1 Polarization of Human Macrophages Using Colloidal Self-Assembled Patterns.
ACS applied materials & interfaces - 2 Aug 2023
Song Jia-Nan, Liu Kun, Mei Jie, Wang Luozixian, Lin Jiao, Du Ping, Liu Yung-Chiang, Wan Yafan, Wong Raymond C B, Yin Ji-Ye, Wang Peng-Yuan
Abstract excerpt
Biophysical and biochemical cues modulate mammalian cell behavior and phenotype simultaneously. Macrophages, indispensable cells in the innate immune system, respond to external threats such as bacterial infections and implanted devices, undergoing the classical M1 polarization to become a pro-inflammatory phenotype. In the study, lipopolysaccharide (LPS)-induced M1 polarization was examined using RAW264.7,...
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