Engineering a reproducible 3D wound model with defined macrophage polarization and partial-thickness mechanical injury

Abstract excerpt

<title>Abstract</title> <p> Despite the acknowledged importance of macrophages in regenerative processes, the field lacks a standardized and reproducible <italic>in-vitro</italic> skin wound model incorporating macrophages, fibroblasts and keratinocytes. To address this, a 3D immunocompetent <italic>in-vitro</italic> wound model based on commercially available cells was established. For the dermal layer, adu...

Topics

Open a Topic to create a Post that cites this publication.

• Dermatologic Treatments and Research
• Dermis
• Diabetes Mellitus
• Inflammation
• Macrophages
• Phenotype
• Wound Healing
• Wound Healing and Treatments

Identifiers and source

Literature Corpus work

4c1138da-16ac-5cb7-bacf-53ed98e8fe0a

DOI

10.21203/rs.3.rs-10548292/v1