Article
Macrophage phenotype switch by sequential action of immunomodulatory cytokines from hydrogel layers on titania nanotubes.
Colloids and surfaces. B, Biointerfaces - 1 Mar 2018
Chen Junhong, Li Mengting, Yang Congling, Yin Xianzhen, Duan Ke, Wang Jianxin, Feng Bo
Abstract excerpt
Inflammatory response occurring between tissues and implants after implantation has attracted increasing attention because it can cause local tissue necrosis and even implant failure. Macrophages play a key role in all stages of inflammation. Pro-inflammatory (M1) and anti-inflammatory (M2) macrophages comprise two main phenotypes and the switch from M1 to M2 at specific time points is important for wound healing...
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