Article
Functional Domains of ZFP809 Essential for Nuclear Localization and Gene Silencing.
PloS one - 1 Jan 2015
Ichida Yu, Utsunomiya Yuko, Yasuda Toru, Nakabayashi Kazuhiko, Sato Toshinori, Onodera Masafumi
Abstract excerpt
Zinc finger protein 809 (ZFP809) is a member of the Kruppel-associated box-containing zinc finger protein (KRAB-ZFP) family, and is highly expressed in mouse immature cells. ZFP809 is known to inhibit the expression of transduced genes driven by Moloney murine leukemia virus (MoMLV)-typed retroviral vectors by binding to the primer binding site (PBS) located downstream of the MLV-long terminal repeat (LTR) of the...
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