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Article

Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteins.

PloS one - 1 Jan 2014

Wang Wei, Cai Jinyang, Lin Yi, Liu Zikou, Ren Qihao, Hu Li, Huang Zan, Guo Mingxiong, Li Wenxin

Abstract excerpt

Multiple nuclear localization domains have been identified in nuclear proteins, and they finely control nuclear import and functions of those proteins. ZNF268 is a typical KRAB-containing zinc finger protein (KRAB-ZFP), and previous studies have shown that the KRAB domain reinforces nuclear localization of KRAB-ZFPs by interacting with KAP1. In this study, we find that some of 24 zinc fingers of ZNF268 also...

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Identifiers

PMID: 24647005
DOI: 10.1371/journal.pone.0092155
PMCID: PMC3960175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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