Article
Effect of the linkers between the zinc fingers in zinc finger protein 809 on gene silencing and nuclear localization.
Biochemical and biophysical research communications - 18 Mar 2016
Ichida Yu, Utsunomiya Yuko, Onodera Masafumi
Abstract excerpt
Zinc finger protein 809 (ZFP809) belongs to the Kruppel-associated box-containing zinc finger protein (KRAB-ZFP) family and functions in repressing the expression of Moloney murine leukemia virus (MoMLV). ZFP809 binds to the primer-binding site (PBS)located downstream of the MoMLV-long terminal repeat (LTR) and induces epigenetic modifications at integration sites, such as repressive histone modifications and de...
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