Article
Interleukin-10 Production in Response to Amyloid-β Differs between Slow and Fast Decliners in Patients with Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2015
Asselineau Delphine, Benlhassan Khadija, Arosio Beatrice, Mari Daniela, Ferri Evelyn, Casati Martina, Gussago Cristina, Tedone Enzo, Annoni Giorgio, Mazzola Paolo, Piette Francois, Belmin Joel, Pariel Sylvie, Bornand Anne, Beaudeux Jean-Louis, Doulazmi Mohamed, Mariani Jean, Bray Dorothy H
Abstract excerpt
We investigated IL-10 and IL-6 production in amyloid-β (Aβ) stimulated peripheral blood mononuclear cells (PBMCs) in twenty Alzheimer's disease (AD) patients with slow progression, eleven with fast progression, and twenty age-matched controls. Promoter polymorphisms in IL-10 (position -592, -819, -1082), IL-6 (-174), transforming growth factor-β1 (TGF-β1) (-10, -25), interferon-γ (IFN-γ) (-874), and tumor...
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