Article
The Association between TNF-alpha, IL-1 alpha and IL-10 with Alzheimer's Disease.
Current Alzheimer research - 1 Jan 2020
Culjak Marija, Perkovic Matea N, Uzun Suzana, Strac Dubravka S, Erjavec Gordana N, Leko Mirjana B, Simic Goran, Tudor Lucija, Konjevod Marcela, Kozumplik Oliver, Mimica Ninoslav, Pivac Nela
Abstract excerpt
BACKGROUND: Sporadic Alzheimer's Disease (AD) is assumed to be associated with different biological/genetic vulnerability, as well as with neuroinflammation, mediated by cytokines. The present study evaluated the role of cytokines in AD. OBJECTIVE: The aim was to determine the possible association of TNF-α (rs1800629), IL1-α (rs1800587) and IL-10 (rs1800896) polymorphisms with AD, and to assess serum TNF-α, IL-1α...
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