Article
Association of interleukin-10 polymorphisms with risk factors of Alzheimer's disease and other dementias (SADEM study).
Immunology letters - 1 Sept 2016
Vargas-Alarcón Gilberto, Juárez-Cedillo Enrique, Martínez-Rodríguez Nancy, Fragoso José Manuel, García-Hernández Normand, Juárez-Cedillo Teresa
Abstract excerpt
Some studies have reported a genetic association between single nucleotide polymorphisms (SNPs) in the promoter region of Interleukin (IL) 10 and Alzheimer's disease (AD), with conflicting results. To further investigate the proposed association and to clarify the role of cytokines as a potential cause for AD susceptibility, we analyzed genotypes, allele distributions and haplotypes of IL-10 promoter...
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