Article
Increased frequency of T cells expressing IL-10 in Alzheimer disease but not in late-onset depression patients.
Progress in neuro-psychopharmacology & biological psychiatry - 2 Dec 2013
Torres Karen Cecília, Araújo Pereira Patrícia, Lima Giselle Sabrina, Bozzi Isadora Cristina, Rezende Vitor Bortolo, Bicalho Maria Aparecida, Moraes Edgar Nunes, Miranda Débora Marques, Romano-Silva Marco Aurélio
Abstract excerpt
Higher risk of dementia is expected for patients with late onset depression (LOD) history. The IL-10 polymorphisms are associated with Alzheimer disease (AD). On the other hand, there is no study associating IL-10 polymorphisms to LOD. This study aimed to investigate the -1082G/A polymorphism association in LOD, AD patients and controls and also the peripheral expression of IL-10 in CD4+ T cells. It was done in a...
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