Article
Association between interleukin-10 polymorphisms and Alzheimer's disease: a systematic review and meta-analysis.
Journal of Alzheimer's disease : JAD - 1 Jan 2012
Di Bona Danilo, Rizzo Claudia, Bonaventura Giuseppe, Candore Giuseppina, Caruso Calogero
Abstract excerpt
It has been hypothesized that polymorphisms of interleukin (IL)-10 genes affect the risk of developing late onset Alzheimer's disease (AD). However, results of different studies are often inconsistent. Our aim was to investigate by meta-analysis the association of the common polymorphisms comprehensively defining the genetic variability of the IL-10 gene with AD risk. Fifteen studies investigating the association...
Topics
- Alzheimer Disease
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Interleukin-10
- Polymorphism, Single Nucleotide
