Article
Interleukin-10 and interleukin-6 gene polymorphisms as risk factors for Alzheimer's disease.
Neurobiology of aging - 1 Sept 2004
Arosio Beatrice, Trabattoni Daria, Galimberti Lorenza, Bucciarelli Paolo, Fasano Francesca, Calabresi Carmen, Cazzullo Carlo Lorenzo, Vergani Carlo, Annoni Giorgio, Clerici Mario
Abstract excerpt
In the pathogenesis of Alzheimer disease (AD), it has been proposed that the anti-inflammatory interleukins such as IL-10 regulate beta-amyloid-induced microglial inflammatory responses inhibiting the proinflammatory cytokine IL-6. Since the promoters of the IL-10 and IL-6 genes show single nucle...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
