Article
Increased expression of NAMPT in PBMC from patients with acute coronary syndrome and in inflammatory M1 macrophages.
Atherosclerosis - 1 Nov 2015
Halvorsen Bente, Espeland Martine Z, Andersen Geir Øystein, Yndestad Arne, Sagen Ellen Lund, Rashidi Azita, Knudsen Eva C, Skjelland Mona, Skagen Karolina R, Krohg-Sørensen Kirsten, Holm Sverre, Ritschel Vibeke, Holven Kirsten B, Biessen Erik A L, Aukrust Pål, Dahl Tuva B
Abstract excerpt
AIM: The aim of the present study were to elucidate the role of NAMPT in atherosclerosis, by examine NAMPT expression in peripheral blood mononuclear cells (PBMC) in patients with coronary artery disease (CAD) and healthy controls and by examining the regulation and effect of NAMPT on macrophage polarization, hypothesizing that it could influence the polarization to inflammatory and resolving macrophages. METHOD...
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