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Article

NLRP3 and downstream cytokine expression elevated in the monocytes of patients with coronary artery disease

1 Jan 2014

Abstract excerpt

INTRODUCTION: Pattern recognition receptor (PRR)-mediated signaling pathways have recently been elucidated to bridge the innate immune system and atherosclerosis. NLRP3 is among the family members of NOD-like receptors (NLRs), a type of PRRs. At present, most studies about the NLRP3 inflammasome focus on animal models and immune cells. Limited information is available regarding the role of NLRP3 in patients with...

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PMID: 25276166
DOI: 10.5114/aoms.2014.44871

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