Article
Bioinformatics approach to evaluate differential gene expression of M1/M2 macrophage phenotypes and antioxidant genes in atherosclerosis.
Cell biochemistry and biophysics - 1 Nov 2014
da Rocha Ricardo Fagundes, De Bastiani Marco Antônio, Klamt Fábio
Abstract excerpt
Atherosclerosis is a pro-inflammatory process intrinsically related to systemic redox impairments. Macrophages play a major role on disease development. The specific involvement of classically activated, M1 (pro-inflammatory), or the alternatively activated, M2 (anti-inflammatory), on plaque formation and disease progression are still not established. Thus, based on meta-data analysis of public micro-array...
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