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Article

Education and APOE-e4 in longitudinal cognitive decline: MacArthur Studies of Successful Aging.

The journals of gerontology. Series B, Psychological sciences and social sciences - 1 Mar 2005

Seeman Teresa E, Huang Mei-Hua, Bretsky Philip, Crimmins Eileen, Launer Lenore, Guralnik Jack M

Abstract excerpt

Longitudinal data from the MacArthur Study of Successful Aging were used to test for interactions between education and apolipoprotein E (APOE) genotype with respect to time trends in cognitive performance. Interactions between education, APOE-e4 status, and time were found for overall cognitive function, and for subscales measuring memory and naming: The presence of the e4 allele was associated with steeper...

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Source

Identifiers

PMID: 15746021
DOI: 10.1093/geronb/60.2.p74

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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