Article
Cognitive ability at age 11 and 70 years, information processing speed, and APOE variation: the Lothian Birth Cohort 1936 study.
Psychology and aging - 1 Mar 2009
Luciano Michelle, Gow Alan J, Harris Sarah E, Hayward Caroline, Allerhand Mike, Starr John M, Visscher Peter M, Deary Ian J
Abstract excerpt
The e4 allele of the apolipoprotein E (APOE) gene confers risk of Alzheimer's disease and, in some studies, relates to cognitive ability and decline in older people without Alzheimer's disease. Its relationship with processing speed, a contributor to cognitive decline with age, is largely unknown. This study tests the association of APOE with cognition and speed, with and without covarying childhood mental...
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