Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge

3 Sept 2015

Abstract excerpt

Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling, and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiation can be triggered by multiple stimuli. To develop anti-fibrotic therapies, it is of paramount importance to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genital Health and Disease
Share to Hippo pathway signaling and YAP/TAZ

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 26389119
DOI: 10.3389/fmed.2015.00059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ ConvergePMID 26389119Read ↗

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.Semantic proximity Read ↗

YAP/TAZ inhibition refines TGF-β signaling to prevent laryngeal fibrosisSemantic proximity Read ↗

TGF-β SIGNAL TRANSDUCTIONSemantic proximity Read ↗

Signal Transduction by the TGF-β SuperfamilySemantic proximity Read ↗

TGFβ signaling in cartilage development and maintenanceSemantic proximity Read ↗

Cellular and molecular mechanisms in fibrosisSemantic proximity Read ↗

Wnt/β-Catenin Signaling: a Promising New Target for Fibrosis DiseasesSemantic proximity Read ↗

TGF-β signaling in health and diseaseSemantic proximity Read ↗

The roles and regulatory mechanisms of TGF-β and BMP signaling in bone and cartilage development, homeostasis and diseaseSemantic proximity Read ↗

TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.Semantic proximity Read ↗

TGF-β/SMAD Pathway and Its Regulation in Hepatic FibrosisSemantic proximity Read ↗

TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.