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Article

TGFβ signaling in cartilage development and maintenance

1 Mar 2014

Abstract excerpt

Members of the transforming growth factor beta (TGFβ) superfamily of secreted factors play essential roles in nearly every aspect of cartilage formation and maintenance. However, the mechanisms by which TGFβs transduce their effects in cartilage in vivo remain poorly understood. Mutations in several TGFβ family members, their receptors, extracellular modulators, and intracellular transducers have been described,...

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PMID: 24677722
DOI: 10.1002/bdrc.21058

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