Article
TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.
Clinical science (London, England : 1979) - 1 Sept 2011
Santibañez Juan F, Quintanilla Miguel, Bernabeu Carmelo
Abstract excerpt
The TGF-β (transforming growth factor-β) system signals via protein kinase receptors and Smad mediators to regulate a plethora of biological processes, including morphogenesis, embryonic development, adult stem cell differentiation, immune regulation, wound healing and inflammation. In addition, alterations of specific components of the TGF-β signalling pathway may contribute to a broad range of pathologies such...
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