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Article

Wnt/β-Catenin Signaling: a Promising New Target for Fibrosis Diseases

17 Aug 2012

Abstract excerpt

Wnt/beta-catenin signaling is involved in virtually every aspect of embryonic development and also controls homeostatic self-renewal in a number of adult tissues. Recently, emerging evidence from researches of organ fibrosis suggest that sustained Wnt/beta-catenin pathway reactivation is linked to the pathogenesis of fibrotic disorders. Here we focus on Wnt/beta-catenin-related pathogenic effects in different...

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PMID: 22670697
DOI: 10.33549/physiolres.932289

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