Article
HLA Class I Alleles Associated with Mortality in Thai Military Recruits with HIV-1 CRF01_AE Infection.
AIDS research and human retroviruses - 1 Jan 2016
Gandhi Rajesh T, Bosch Ronald J, Rangsin Ram, Chuenchitra Thippawan, Sirisopana Narongrid, Kim Jerome H, Robb Merlin L, Vejbaesya Sasijit, Paris Robert M, Nelson Kenrad E
Abstract excerpt
In HIV-1-infected patients, variation at the HLA class I locus is associated with disease progression, but few studies have assessed the influence of HLA alleles on HIV-1 CRF01_AE infection, which is dominant in Thailand. We hypothesized that alleles predicted to confer more effective immune responses, such as HLA-B*46, would protect against disease progression. HLA typing was performed on HIV-1 incident cases...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.