Article
Associations between HLA frequencies and pathogenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam cohort of homosexual men.
The Journal of infectious diseases - 1 Jun 1994
Klein M R, Keet I P, D'Amaro J, Bende R J, Hekman A, Mesman B, Koot M, de Waal L P, Coutinho R A, Miedema F
Abstract excerpt
HLA-disease associations may be important for understanding the pathogenesis of human immunodeficiency virus type 1 (HIV-1) infection. Therefore, 106 homosexual men from the Amsterdam Cohort Study on AIDS with a known date of HIV-1 seroconversion were serologically typed for HLA. Several significant associations between HLA type and pathogenic features of HIV-1 infection were observed: Subjects with fever and...
Topics
- Cohort Studies
- Follow-Up Studies
- HIV Seropositivity
- HIV-1
- HLA Antigens
- Homosexuality
- Humans
- Male
- Netherlands
- Phenotype