Article
Tools and best practices for data processing in allelic expression analysis.
Genome biology - 17 Sept 2015
Castel Stephane E, Levy-Moonshine Ami, Mohammadi Pejman, Banks Eric, Lappalainen Tuuli
Abstract excerpt
Allelic expression analysis has become important for integrating genome and transcriptome data to characterize various biological phenomena such as cis-regulatory variation and nonsense-mediated decay. We analyze the properties of allelic expression read count data and technical sources of error, such as low-quality or double-counted RNA-seq reads, genotyping errors, allelic mapping bias, and technical covariates...
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