Article
Key considerations for measuring allelic expression on a genomic scale using high-throughput sequencing.
Molecular ecology - 1 Mar 2010
Fontanillas Pierre, Landry Christian R, Wittkopp Patricia J, Russ Carsten, Gruber Jonathan D, Nusbaum Chad, Hartl Daniel L
Abstract excerpt
Differences in gene expression are thought to be an important source of phenotypic diversity, so dissecting the genetic components of natural variation in gene expression is important for understanding the evolutionary mechanisms that lead to adaptation. Gene expression is a complex trait that, in diploid organisms, results from transcription of both maternal and paternal alleles. Directly measuring allelic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
