Estimating the Allele-Specific Expression of SNVs From 10× Genomics Single-Cell RNA-Sequencing Data.

doi:10.3390/genes11030240

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Article

Estimating the Allele-Specific Expression of SNVs From 10× Genomics Single-Cell RNA-Sequencing Data.

Genes - 25 Feb 2020

M Prashant N, Liu Hongyu, Bousounis Pavlos, Spurr Liam, Alomran Nawaf, Ibeawuchi Helen, Sein Justin, Reece-Stremtan Dacian, Horvath Anelia

Abstract excerpt

With the recent advances in single-cell RNA-sequencing (scRNA-seq) technologies, the estimation of allele expression from single cells is becoming increasingly reliable. Allele expression is both quantitative and dynamic and is an essential component of the genomic interactome. Here, we systematically estimate the allele expression from heterozygous single nucleotide variant (SNV) loci using scRNA-seq data...

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PMID: 32106453
DOI: 10.3390/genes11030240
PMCID: PMC7140866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.