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Article

Allelic mapping bias in RNA-sequencing is not a major confounder in eQTL studies.

Genome biology - 20 Sept 2014

Panousis Nikolaos I, Gutierrez-Arcelus Maria, Dermitzakis Emmanouil T, Lappalainen Tuuli

Abstract excerpt

BACKGROUND: RNA sequencing (RNA-seq) is the current gold-standard method to quantify gene expression for expression quantitative trait locus (eQTL) studies. However, a potential caveat in these studies is that RNA-seq reads carrying the non-reference allele of variant loci can have lower probabil...

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Share to Chromosome Mapping
Share to Genetic Association Studies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

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Share to Sequence Alignment

Share to Sequence Analysis, RNA

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Identifiers

PMID: 25239376
DOI: 10.1186/s13059-014-0467-2
PMCID: PMC4212091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25239376-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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