Article
Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine.
AIDS (London, England) - 24 Aug 2015
Blasi Maria, Carpenter J Harris, Balakumaran Bala, Cara Andrea, Gao Feng, Klotman Mary E
Abstract excerpt
OBJECTIVE: HIV-1 persists indefinitely in memory CD4 T cells and other long-lived cellular reservoirs despite antiretroviral therapy. Our group had previously demonstrated that HIV-1 can establish a productive infection in renal epithelial cells and that the kidney represents a separate compartment for HIV-1 replication. Here, to better understand the viruses in this unique site, we genetically characterized and...
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