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Article

Compartmentalization of HIV-1 within the female genital tract is due to monotypic and low-diversity variants not distinct viral populations.

PloS one - 22 Sept 2009

Bull Marta, Learn Gerald, Genowati Indira, McKernan Jennifer, Hitti Jane, Lockhart David, Tapia Kenneth, Holte Sarah, Dragavon Joan, Coombs Robert, Mullins James, Frenkel Lisa

Abstract excerpt

BACKGROUND: Compartmentalization of HIV-1 between the genital tract and blood was noted in half of 57 women included in 12 studies primarily using cell-free virus. To further understand differences between genital tract and blood viruses of women with chronic HIV-1 infection cell-free and cell-associated virus populations were sequenced from these tissues, reasoning that integrated viral DNA includes variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19771165
DOI: 10.1371/journal.pone.0007122
PMCID: PMC2741601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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