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Article

Analysis of variability of urinary excreted JC virus strains in patients infected with HIV and healthy donors.

Journal of neurovirology - 1 Jun 2018

Karalic Danijela, Lazarevic Ivana, Banko Ana, Cupic Maja, Jevtovic Djordje, Jovanovic Tanja

Abstract excerpt

In immunocompromised individuals, especially in patients with T cell immunodeficiency, reactivation of JCPyV can cause serious life-threatening diseases. Nowadays, HIV infection is one of the most important factor for reactivation of JCPyV and the development of of the progressive multifocal leukoencephalopathy (PML). Mutations in the outer loops of the VP1 region can lead to the selection of the viral variants...

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Share to Antiretroviral Therapy, Highly Active
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukoencephalopathy, Progressive Multifocal

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Source

Identifiers

PMID: 29243131
DOI: 10.1007/s13365-017-0608-y

Genes

PML

Provenance

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