Article
Human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood: compartmentalization and intrapatient recombination.
Journal of virology - 1 Jan 2005
Philpott Sean, Burger Harold, Tsoukas Christos, Foley Brian, Anastos Kathryn, Kitchen Christina, Weiser Barbara
Abstract excerpt
Investigation of human immunodeficiency virus type 1 (HIV-1) in the genital tract of women is crucial to the development of vaccines and therapies. Previous analyses of HIV-1 in various anatomic sites have documented compartmentalization, with viral sequences from each location that were distinct yet phylogenetically related. Full-length RNA genomes derived from different compartments in the same individual,...
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