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Quasispecies Analysis of JC Virus DNA Present in Urine of Healthy Subjects

15 Aug 2013

Abstract excerpt

JC virus is a human polyomavirus that infects the majority of people without apparent symptoms in healthy subjects and it is the causative agent of progressive multifocal leucoencephalopathy (PML), a disorder following lytic infection of oligodendrocytes that mainly manifests itself under immunosuppressive conditions. A hallmark for JC virus isolated from PML-brain is the presence of rearrangements in the...

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PMID: 23967139
DOI: 10.1371/journal.pone.0070950

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