Article
Human immunodeficiency virus in semen arises from a genetically distinct virus reservoir.
AIDS research and human retroviruses - 1 Apr 1998
Kiessling A A, Fitzgerald L M, Zhang D, Chhay H, Brettler D, Eyre R C, Steinberg J, McGowan K, Byrn R A
Abstract excerpt
The reservoir of human immunodeficiency virus (HIV) in semen is unknown. Several lines of evidence suggest that semen HIV may not arise from the same reservoir of infection as peripheral blood. If true, the viral burden in the two compartments could be qualitatively and quantitatively different, a scenario of potentially profound significance for the design of effective strategies of treatment, disease...
Topics
- Amino Acid Sequence
- Cohort Studies
- Disease Reservoirs
- Genetic Variation
- HIV
- HIV Infections
- HIV Protease
- HIV Protease Inhibitors
- Humans
- Leukocyte Count
- Leukocytes