Article
Detection and molecular characterization of urinary tract HIV-1 populations.
Annals of clinical microbiology and antimicrobials - 24 Sept 2019
Mzingwane M L, Hunt G, Lassauniere R, Kalimashe M, Bongwe A, Ledwaba J, Chaisson R E, Martinson N, Richter K, Bowyer S M, Tiemessen C T
Abstract excerpt
BACKGROUND: Identification of all possible HIV reservoirs is an important aspect in HIV eradication efforts. The urinary tract has however not been well studied as a potential HIV reservoir. In this pilot study we molecularly characterized HIV-1 viruses in urine and plasma samples to investigate HIV-1 replication, compartmentalization and persistence in the urinary tract. METHODS: Prospectively collected urine...
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