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Article

Impact of seminal cytomegalovirus replication on HIV-1 dynamics between blood and semen.

Journal of medical virology - 1 Nov 2012

Gianella Sara, Mehta Sanjay R, Strain Matthew C, Young Jason A, Vargas Milenka V, Little Susan J, Richman Douglas D, Kosakovsky Pond Sergei L, Smith Davey M

Abstract excerpt

The genital tract of individuals infected with human immunodeficiency virus type 1 (HIV-1) is an anatomic compartment that supports local HIV-1 and cytomegalovirus (CMV) replication. This study investigated the association of seminal CMV replication with changes in HIV-1 clonal expansion, evolution and phylogenetic compartmentalization between blood and semen. Fourteen paired blood and semen samples were analyzed...

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Source

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Identifiers

PMID: 22997072
DOI: 10.1002/jmv.23398
PMCID: PMC3472447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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