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Article

Towards a Next-Generation Sequencing Diagnostic Service for Tumour Genotyping: A Comparison of Panels and Platforms.

BioMed research international - 1 Jan 2015

Burghel George J, Hurst Carolyn D, Watson Christopher M, Chambers Phillip A, Dickinson Helen, Roberts Paul, Knowles Margaret A

Abstract excerpt

Detection of clinically actionable mutations in diagnostic tumour specimens aids in the selection of targeted therapeutics. With an ever increasing number of clinically significant mutations identified, tumour genetic diagnostics is moving from single to multigene analysis. As it is still not feasible for routine diagnostic laboratories to perform sequencing of the entire cancer genome, our approach was to...

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Identifiers

PMID: 26351634
DOI: 10.1155/2015/478017
PMCID: PMC4553307

Genes

OGT
BRAF
EGFR
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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