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Article

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors.

Journal of visualized experiments : JoVE - 20 Sept 2016

Fox Alan J, Hiemenz Matthew C, Lieberman David B, Sukhadia Shrey, Li Barnett, Grubb Joseph, Candrea Patrick, Ganapathy Karthik, Zhao Jianhua, Roth David, Alley Evan, Loren Alison, Morrissette Jennifer J D

Abstract excerpt

As our understanding of the driver mutations necessary for initiation and progression of cancers improves, we gain critical information on how specific molecular profiles of a tumor may predict responsiveness to therapeutic agents or provide knowledge about prognosis. At our institution a tumor genotyping program was established as part of routine clinical care, screening both hematologic and solid tumors for a...

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Identifiers

PMID: 27684276
DOI: 10.3791/52758
PMCID: PMC5092039

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