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Article

Development and evaluation of ActSeq: A targeted next-generation sequencing panel for clinical oncology use.

PloS one - 1 Jan 2022

Shi Zonggao, Lopez Jacqueline, Kalliney William, Sutton Bobbie, Simpson Joyce, Maggert Kevin, Liu Sheng, Wan Jun, Stack M Sharon

Abstract excerpt

PURPOSE: The demand for high-throughput genetic profiling of somatic mutations in cancer tissues is growing. We sought to establish a targeted next generation sequencing (NGS) panel test for clinical oncology practice. METHODS: Customized probes were designed to capture exonic regions of 141 genes selected for the panel, which was aimed for the detection of clinically actionable genetic variations in cancer,...

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Identifiers

PMID: 35446881
DOI: 10.1371/journal.pone.0266914
PMCID: PMC9022865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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