Article
JHDM1D and HDAC1-3 mRNA expression levels in peripheral blood mononuclear cells of patients with systemic lupus erythematosus.
Zeitschrift fur Rheumatologie - 1 Dec 2015
Nawrocki M J, Strugała A J, Piotrowski P, Wudarski M, Olesińska M, Jagodziński P P
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic relapsing autoimmune disease characterized by production of autoantibodies against a series of nuclear antigens and by chronic inflammation. The etiology of SLE is the result of interactions between genetic, epigenetic, hormonal, and environmental factors. Changes in histone acetylation and methylation contribute to structural chromatin modifications....
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