Article
Effects of Major Epigenetic Factors on Systemic Lupus Erythematosus
27 May 2018
Abstract excerpt
The pathogenesis of systemic lupus erythematosus (SLE) is influenced by both genetic factors and epigenetic modifications; the latter is a result of exposure to various environmental factors. Epigenetic modifications affect gene expression and alter cellular functions without modifying the genomic sequences. CpG-DNA methylation, histone modifications, and miRNAs are the main epigenetic factors of gene regulation....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
