Article
Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians.
Obesity (Silver Spring, Md.) - 1 Oct 2015
Muller Yunhua L, Hanson Robert L, Wiessner Gregory, Nieboer Lori, Kobes Sayuko, Piaggi Paolo, Abdussamad Mahdi, Okani Chidinma, Knowler William C, Bogardus Clifton, Baier Leslie J
Abstract excerpt
OBJECTIVE: A prior genome-wide association study (GWAS) in Pima Indians identified variation within FOXO1A that modestly associated with early-onset (onset age < 25 years) type 2 diabetes (T2D). FOXO1A encodes the forkhead transcription factor involved in pancreatic β-cell growth and hypothalamic...
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