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Article

The FOXO1 Gene-Obesity Interaction Increases the Risk of Type 2 Diabetes Mellitus in a Chinese Han Population.

Journal of Korean medical science - 1 Feb 2017

Gong Lilin, Li Rong, Ren Wei, Wang Zengchan, Wang Zhihong, Yang Maosheng, Zhang Suhua

Abstract excerpt

Here, we aimed to study the effect of the forkhead box O1-insulin receptor substrate 2 (FOXO1-IRS2) gene interaction and the FOXO1 and IRS2 genes-environment interaction for the risk of type 2 diabetes mellitus (T2DM) in a Chinese Han population. We genotyped 7 polymorphism sites of FOXO1 gene and IRS2 gene in 780 unrelated Chinese Han people (474 cases of T2DM, 306 cases of healthy control). The risk of T2DM in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28049237
DOI: 10.3346/jkms.2017.32.2.264
PMCID: PMC5219992

Genes

FOXO1
IRS2

Provenance

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