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Article

Analysis of FOXO1A as a candidate gene for type 2 diabetes.

Molecular genetics and metabolism - 1 Jun 2006

Karim Mohammad A, Craig Rebekah L, Wang Xiaoqin, Hale Terri C, Elbein Steven C

Abstract excerpt

The human forkhead box O1A (FOXO1A) gene on chromosome 13q14.1 is a key transcription factor in insulin signaling in liver and adipose tissue and plays a central role in the regulation of key pancreatic beta-cell genes including IPF1. We hypothesized that sequence variants of FOXO1A contribute to the observed defects in hepatic and peripheral insulin action and altered beta-cell compensation that characterize...

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Source

Identifiers

PMID: 16497530
DOI: 10.1016/j.ymgme.2006.01.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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